Much of the recent research concerning mild traumatic brain injury (mTBI) has focused on professional athletes and military veterans. This research may not apply to individuals with mTBI whose injuries result from other causes, including motor vehicle collisions and falls.
Autopsies of individuals with these types of injuries indicate that mTBI causes diffuse axonal injury and micro hemorrhages. Until recently, however, it was not possible to examine microstructural pathology in living persons because of the insufficient sensitivity of computed tomography and conventional magnetic resonance imaging (MRI). Thus, researchers were not able to explore any relationship between mTBI-related structural neuropathology and mTBI-related dysfunction, specifically cognitive impairment.