Advances In Neuroimaging
At present, the gold standard for objectively proving that an individual sustained a mild traumatic brain injury is through neuropsychological testing. As we know, standard diagnostic testing such as CT scans, MRIs and EEGs, due to their lack of sensitivity, rarely if ever detect brain abnormalities in patients with mild traumatic brain injury.
However, advances in neuroimaging may soon eliminate the need for neuropsychological testing to diagnose brain damage. Advances in FMRI and diffusion tensor imaging (DTI) will soon become the gold standard.
I recently read an article published in Brain entitled “Structural Dissociation of Attentional Control and Memory in Adults with and without Mild Traumatic Brain Injury”. The article by S. N. Niogi et al, noted that executive function such as attention and memory are among the most significant human brain processes impacting overall cognitive function. The study contained 43 patients prospectively recruited with mild TBI, (28 males, 15 females) who were imaged at least one month post injury and 23 healthy volunteers, (17 males, 6 females). There was no significant difference in mean age, gender, handedness, or level of education between the mild TBI group and the control group. Those with a prior history of TBI, a history of neurological or psychiatric illness were excluded. All subjects underwent diffusion tensor imaging along with conventional MRI. The study provided clear evidence that DTI may serve as a microstructural imaging biomarker for cognitive dysfunctions and variations within normal cognitive functions. Hopefully, further research will confirm this finding. DTI has already been accepted in our courts as a reliable neuroimaging mechanism to detect brain injury from trauma. Further studies such as this will only strengthen its admissibility.
More than half of Toronto's homeless population have experienced severe trauma
A new study states that prior to becoming homeless, more than one out of every three of Toronto, Canada’s homeless had suffered from a traumatic brain injury, which furthers past theories that mental health is linked to homelessness.
A paper published in the Canadian Medical Association Journal recently found that more than half of the homeless population of Toronto had experienced a severe brain injury, and 70% of those did so before ending up on the streets. The study surveyed roughly 900 people living in Toronto homeless shelters from 2004 – 2005. Traumatic brain injuries usually result in cognitive impairment, attention deficits and emotional instability.
You can read more on this story here.
Neuropsychological Evaluation In The Diagnosis And Management of Sports-Related Concussions
Causes and High Risk of TBIs
- Falls - 28%
- Motor vehicle-traffic crashes - 20%
- Stuck by/against events - 19%
- Assaults - 11%
Although a traumatic brain injury can happen to almost anyone, almost anywhere, the National Center for Injury Prevention in association with the Centers for Disease Control and Prevention have studied who is most at risk of suffering a traumatic brain injury:
- Males are about 1.5 times as likely as females to suffer from a TBI
- The two age groups at highest risk for a TBI are 0-4 years of age, and 15-19 years of age
- Certain military duties (i.e. paratrooper) increase the risk of sustaining a TBI
- African Americans have the highest death rate from TBIs
Veterans Medical Care
Looking for a silver lining in a dark cloud, maybe these unfortunate events will help people to understand that one can sustain a brain injury without loss of consciousness and with no visible sign of injury.
Glasgow Coma Scale in Pre-verbal Children
I read an interesting article this morning on the Use of the Pediatric Glasgow Coma Scale in Pre-verbal Children with Blunt Head Trauma. James F. Holmes, M.D. MPH and his colleagues from the University of California, Davis, School of Medicine, investigated whether the accuracy of pediatric Glasgow Coma Scale score in pre-verbal children with blunt head trauma compared favorably with the standard glasgo coma scale score in older children. The authors perspectively enrolled children younger than 18 years with blunt head trauma.
According to the study, the patients were divided into cohorts of two years and younger and those older than two years. The authors assigned a pediatric GCS score to the younger cohort and the standard GSC score to the older cohort. The authors concluded that the pediatric Glasgow Coma Scale for children two years and younger compared favorably with the standard GCS in the evaluation of children with blunt head trauma. The Pediatric GCS was found to be particularly accurate in evaluating pre-verbal children with blunt head trauma with regard to the need for acute intervention. Acad Emerg Med Volume 12, Number 9 814-819 (2005).
Post-Concussion Syndrome
Following up on earlier posts (here, here, here, here, here, here, and finally here) regarding seemingly minor injuries (a bump to the head or a fender bender) can actually be major events which sometimes may cause irreversible damage to the individual's health and personality.
When events such as a fall or minor car accident take place, many people "shake off the injury" and believe that no permanent damage has been done. As such, most do not go to their doctor or the hospital for treatment. Even those who do go to their doctor may be misdiagnosed since MRIs and CAT scans usually can not detect the damage done to blood vessels and tissues in the injured person's head.
Post-concussion syndrome refers to the changes in an injured person's brain processes that affect personality, mood, memory, social interaction and the ability to work and learn. Post-concussion syndrome can result in mental rigidity, inattention, swinging moods and shifting energy levels.
But doctors often miss the diagnosis of post-concussion syndrome, because it is not as recognizable as a broken bone or tumor. The patient may be as smart as ever, in fact. But he or she may have become "socially disabled" - impulsive, disinhibited, likely to say things out of context or inappropriately, unable to start a relationship or maintain one.
This can often be the basis for damage awards in a lawsuit, said Dr. Gerald Tramontano, whose NeuroRehab Institute includes a "forensic division," whose experts testify in court.
You can read more about Post-concussion syndrome here.
Double Vision After a Traumatic Brain Injury
After one suffers a traumatic brain injury, many additional physical problems can occur as a result including vision problems. After traumatic brain injury, it is possible for the nerves or muscles that control eye movement to be injured. It is possible for the victim of a brain injury to experience a visual impairment such as double vision (diplopia), or the occurrence of two images at the same time. This condition can affect reading, walking, driving and other daily activities. In some cases, double vision isn't constant and the symptoms may only occur during certain settings.
There are two types of double vision: monocular and binocular. In monocular double vision, the vision problem affects only one eye and does not go away when looking in different directions. When the affected eye is covered, the double images disappear. Binocular double vision affects both eyes.
Chiari malformation (4)
Today will be my fourth and final post on Chiari malformation.
While it is generally believed that Chiari malformation occurs at birth, recent scientific research has shown that this condition, which may be asymptomatic, can become symptomatic due to trauma. Also, there is a body of literature that recognizes that Chiari malformation may become acquired as opposed to congenital.
Chiari malformation (3)
The ideology of Chiari malformations is generally believed to be that the malformation is present at birth. [It has been suggested that during early embryo development of the brainstem and spinal cord, the malformation occurs.] While this condition may be asymptomatic in many people, it can, over time, become symptomatic. It is noteworthy that Chiari I malformation occurs more often in women than in men.
