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Brain's Resting State Upset by Mild Head Injury

MedPage Today (11/24, Phend) reported, "Mild traumatic brain injury (TBI) disrupts the brain's 'default mode' in a way that shows up on functional MRI and correlates with symptoms," according to a small study published in the December issue of the journal Radiology. Investigators found that, "compared with normal controls, patients with posttraumatic symptoms soon after mild TBI showed reduced connectivity in some regions, and increased connectivity in others within the network that the brain uses during inactivity for information processing and maintenance." The researchers reported that "these abnormalities were associated with cognitive dysfunction, depression, anxiety, fatigue, and post-concussion syndrome."

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